Publication: Polarization sensitive imaging of glaucoma surgery

Our collaborator Shinichi Fukuda recently reported his comparative study among optical coherence tomography (OCT), conventional polarization sensitive OCT (PS-OCT's phase retardation imaging) and our new PS-OCT imaging method, i.e., birefringence imaging findings of bleb structure created in glaucoma surgery. As he concluded, the phase retardation imaging is particularly sensitive to slight alteration of bleb tissue, where as the birefringence imaging can highlight localized alteration of the tissue. He also found that the birefringence imaging can visualize "plate-like birefringence change" in the bleb, and it is associated with poor outcome of the surgery.

The details of study is described in Scientific Reports.

>> Full length article (open access)

S. Fukuda, A. Fujita, D. Kasaragod, S. Beheregaray, Y. Ueno, Y. Yasuno, and T. Oshika, ``Comparison of intensity, phase retardation, and local birefringence images for filtering blebs using polarization-sensitive optical coherence tomography,'' Scientific Reports 8, 7519 (2018).

筑波大学眼科の福田慎一先生が、私達との共同研究である「緑内障手術痕の光干渉断層計（OCT）、偏光位相差トモグラフィー、複屈折トモグラフィー観察の比較」に関して Scientific Reports 誌で報告しています。この研究によって、偏光位相差トモグラフィーは緑内障手術痕における組織のごく弱い変化を検出することが可能であり、一方、複屈折トモグラフィーは組織の局所的な変化をとらえられることがわかりました。また、複屈折トモグラフィーで手術痕を観察したさい見られることのある「プレート状複屈折構造」が、手術予後不良を示す指標になることがしめされました。

この研究の詳細は Scientific Reports 誌で報告されています。

>> Full length article (open access)

S. Fukuda, A. Fujita, D. Kasaragod, S. Beheregaray, Y. Ueno, Y. Yasuno, and T. Oshika, ``Comparison of intensity, phase retardation, and local birefringence images for filtering blebs using polarization-sensitive optical coherence tomography,'' Scientific Reports 8, 7519 (2018).